Table 2 Number of steps taken before the mean exceeds certain internal and external thresholds (earliest sample exceeding threshold is shown in brackets)
| Â | Threshold | Number of steps required for optimization beyond prior at a given threshold | Number of steps required for optimization beyond external thresholds | ||||||
|---|---|---|---|---|---|---|---|---|---|
120% | 140% | 160% | 180% | 200% | Inactive mean | Active mean | 80% precision threshold | ||
DRD2 | REINVENT | > 500 (15) | > 500 (685) | > 500 (22,292) | > 500 (> 32,000) | > 500 (> 32,000) | 1 (1) | 163 (15) |  > 500 (15) |
Augmented Hill-Climb + DF2 | 19 (2) | 6 (49) | 105 (1248) | > 500 (3009) | > 500 (23,150) | 2 (2) | 19 (2) | 48 (2) | |
OPRM1 | REINVENT | 133 (7) | > 500 (868) | > 500 (7663) | > 500 (> 32,000) | > 500 (> 32,000) | 4 (2) | 80 (4) | > 500 (7) |
Augmented Hill-Climb + DF2 | 3 (16) | 17 (22) | 45 (29) | 150 (34) | > 500 (2759) | 6 (16) | 17 (22) | 33 (28) | |
AGTR1 | REINVENT | > 500 (25) | > 500 (510) | > 500 (5,596) | > 500 (> 32,000) | > 500 (> 32,000) | 1 (2) | > 500 (8) | 419 (6) |
Augmented Hill-Climb + DF2 | 62 (27) | 318 (869) | 396 (3,404) | > 500 (5,207) | > 500 (27,979) | 2 (1) | 62 (27) | 46 (2) | |
OX1R | REINVENT | 5 (1) | 52 (1) | > 500 (7) | > 500 (142) | > 500 (490) | 1 (2) | 9 (1) | > 500 (490) |
Augmented Hill-Climb + DF2 | 9 (1) | 15 (2) | 31 (2) | 87 (31) | 382 (557) | 2 (1) | 14 (2) | 494 (557) | |
Average fold improvement | 19.8 (2.5) | 11.2 (38.7) | 8.3 (71.8) | 2.8 (240.6) | 1.1 (3.8) | 0.5 (1.0) | 5.5 (2.1) | 9.7 (3.2) | |