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Table 3 Independent test results of different stacked models on the independent test dataset

From: DeepAR: a novel deep learning-based hybrid framework for the interpretable prediction of androgen receptor antagonists

Meta-model

ACC

Sn

Sp

MCC

AUC

F1

DeepAR

0.911

0.897

0.927

0.823

0.945

0.912

RF

0.888

0.862

0.915

0.777

0.941

0.888

LGBM

0.888

0.885

0.890

0.775

0.947

0.890

SVMRBF

0.864

0.851

0.878

0.728

0.913

0.865

XGB

0.864

0.839

0.890

0.729

0.949

0.864

LR

0.893

0.874

0.915

0.788

0.949

0.894

PLS

0.893

0.874

0.915

0.788

0.951

0.894

NB

0.888

0.862

0.915

0.777

0.906

0.888

ET

0.899

0.897

0.902

0.799

0.952

0.902

MLP

0.876

0.839

0.915

0.754

0.927

0.874

KNN

0.834

0.816

0.854

0.670

0.835

0.835

SVMLN

0.846

0.816

0.878

0.694

0.913

0.845

ADA

0.858

0.828

0.890

0.718

0.922

0.857

DT

0.822

0.816

0.829

0.645

0.823

0.826