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Fig. 5 | Journal of Cheminformatics

Fig. 5

From: 3DDPDs: describing protein dynamics for proteochemometric bioactivity prediction. A case for (mutant) G protein-coupled receptors

Fig. 5

PCM model performance with dynamic and non-dynamic protein descriptor combination in regression tasks with a temporal split. In green, the performance of RF models trained on 3DDPDs. In blue, RF models trained on non-dynamic protein descriptors. In green and blue, RF models trained on a combination of both types. Zscale Hellberg and van Westen are abbreviated to Zscale H and vW, respectively. The statistical significance of the differences is derived from pairwise Student T-test and represented by asterisks: * = p-value < 0.05; ** = p-value < 0.01; *** = p-value < 0.001

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