Table 2 GPCR mutations selected

AA1R

5UEN

T277A^7.41

13/36

0

–

R291C^7.56

4/4

1

NpxxY (ext)

R296C^8.51

4/4

1

–

AA2AR

5IU4

I66A^2.64

20/22

0

–

L85A^3.33

21/21

0

–

T88D^3.36

14/16

0

–

S91A^3.39

12/16

0

–

L167A^45.51

20/20

0

–

M177A^5.40

22/24

0

–

N181A^5.43

20/20

0

–

W246A^6.48

37/52

0

CWxP

N253A^6.55

22/22

0

–

Y271A^7.35

20/22

0

–

S277A^7.41

29/33

0

–

H278N^7.42

3/3

1

–

ACM2

3UON

D103E^3.32

32/42

0

–

D103N^3.32

12/15

0

–

V421L^7.33

1/1

1

–

ADRB2

2RH1

D79N^2.50

12/12

0

–

D130N^3.49

11/11

0

DRY

S203A^5.43

12/12

0

–

S204A^5.44

13/13

0

–

N293L^6.55

12/12

0

–

V317A^7.43

5/5

1

–

CCR5

4MBS

Y108A^3.32

12/20

0

–