Table 2 The percentage of control (POC) values for the 17 molecules tested at 10 µM using Protein–Ligand binding assay (scanELECT by DiscoverX)
From: Iterative machine learning-based chemical similarity search to identify novel chemical inhibitors
Name | POC (%) | CAS Registry Number |
|---|---|---|
ZINC5814210 | 3.6 | 151266-23-8 |
ZINC5479148 | 15 | 83255-86-1 |
ZINC32911363 | 20 | 1135283-22-5 |
ZINC4023558 | 43 | 42951-65-5 |
ZINC48325380 | 72 | 1223037-63-5 |
ZINC261507424 | 77 | 1640120-88-2 |
ZINC32581883 | 85 | 1125427-49-7 |
ZINC72156820 | 88 | 1360224-51-6 |
ZINC0130101 | 90 | 329712-63-2 |
ZINC16052626 | 91 | 848635-49-4 |
ZINC1573667 | 100 | 2993-05-07 |
ZINC70450773 | 100 | 1338218-78-2 |
ZINC84199299 | 100 | 1378862-01-1 |
ZINC8557584 | 100 | 93352-69-3 |
ZINC81947236 | 100 | 946157-08-0 |
ZINC0061493 | 100 | 2550–73-4 |
ZINC9419630 | 100 | 121371-16-2 |