Fig. 7From: A molecule perturbation software library and its application to study the effects of molecular design constraintsSAScore distributions of RDM using different types of constraints. Medians are shown as black lines. Lower SAScores are indicative of an easier synthesis. Stars on top of the distributions indicate statistically significant differences with the “no constraints” control group. A more detailed statistical analysis can be found in Additional file 1: Table S2Back to article page