Table 4 Regression performance of PMF-CPI in comparison with three representative methods
Methods | MSE \(\downarrow\) | Pearson \(\uparrow\) |
|---|---|---|
DeepAffinity | 0.548 | 0.840 |
DeepDTA | 0.612 | 0.848 |
MONN | 0.584 | 0.858 |
PMF-CPI | 0.474 | 0.884 |
DeepAffinity(Parameter Ensemble) | 0.533 | 0.840 |
DeepAffinity(NN Ensemble) | 0.504 | 0.860 |
DeepDTA(Ensemble of 30 Models) | 0.471 | 0.886 |
MONN(Ensemble of 30 Models) | 0.432 | 0.895 |
PMF-CPI(Parameter Ensemble) | 0.416 | 0.899 |