Table 4 Prediction statistics of reversed Lipinski’s and Veber’s models to predict gut permanence
From: Analysis of metabolites in human gut: illuminating the design of gut-targeted drugs
Pred | Acc | Prec | Rec | F1 | AUROC | AUPRC |
|---|---|---|---|---|---|---|
Lip ext test | 0.862 | 0.966 | 0.849 | 0.903 | NA | NA |
Lip ext test FL | 0.946 | 1 | 0.946 | 0.972 | NA | NA |
Lip ext test noFL | 0.685 | 0.179 | 0.06 | 0.089 | NA | NA |
Lip ext test stand | 0.816 | 0.59 | 0.503 | 0.53 | NA | NA |
Veb ext test | 0.877 | 0.946 | 0.889 | 0.917 | NA | NA |
Veb ext test FL | 0.977 | 1 | 0.977 | 0.988 | NA | NA |
Veb ext test noFL | 0.667 | 0.278 | 0.179 | 0.217 | NA | NA |
Veb ext test stand | 0.822 | 0.639 | 0.578 | 0.602 | NA | NA |