Cobdock: an accurate and practical machine learning-based consensus blind docking method

Table 2 The summary of cavity detection tools used in the CoBDcok

Cavity detection tool	Type	Overview
P2Rank 2.0	Machine learning	P2Rank is a standalone template-free program for machine learning-based prediction of ligand binding sites [15].
Fpocket	Geometric	A pocket detection tool called Fpocket was developed using alpha spheres and Voronoi tessellation [16].

The identification of binding sites has been a challenge in the field of structural research, prompting the development of several binding site methods throughout the years. A subset of individuals were provided with a brief introductory overview

ISSN: 1758-2946