Table 6 Predicted reaction conditions for the Friedel-Crafts alkylation illustrated in Fig. 6B
Rank | Reagent(s) | Solvent(s) | Temperature (\(^{\circ }{} {\textbf {C}}\)) |
|---|---|---|---|
1(\(\checkmark \)) | Silver trifluoromethanesulfonate | Acetonitrile | 16.6 |
2 | Trimethylsilyl trifluoromethanesulfonate | Dichloromethane | 14.3 |
3 | Silver trifluoromethanesulfonate | Dichloromethane | 11.2 |
4 | Trimethylsilyl trifluoromethanesulfonate | Acetonitrile | 15.9 |
5(\(\checkmark \)) | Bismuth(III) trifluoromethanesulfonate | Acetonitrile | 19.4 |
6 | Bismuth(III) trifluoromethanesulfonate | Dichloromethane | 19.4 |
7 | Trimethylsilyl trifluoromethanesulfonate | Acetonitrile; dichloromethane | 13.6 |
8 | Silver trifluoromethanesulfonate | Acetonitrile; dichloromethane | 11.9 |
9 | Bismuth(III) trifluoromethanesulfonate; trimethylsilyl trifluoromethanesulfonate | Dichloromethane | 17.0 |
10 | Bismuth(III) trifluoromethanesulfonate; silver trifluoromethanesulfonate | Dichloromethane | 14.2 |